Original article / research
Prevalence and Trends of Transfusion Transmissible Infections in Blood Donors in a Tertiary Care Centre- An Institutional 4-year Retrospective Study
Dr. Shweta Wasudeo Dhote,
Flat No. 701, Bhairav Signature, Sector 30, 31, CBD Belapur,
Navi Mumbai-400614, Maharashtra, India.
Introduction: In today’s time, safe transfusion begins with the screening and confirmation of availability of healthy donors. An important criterion to make safe blood available for one and for all is to try and prevent Transfusion Transmitted Infections (TTIs); and once if a donor is identified to be reactive for any one of the TTIs, then to notify and counsel them.
Aim: To study the seroprevalence and trends of TTIs in blood donors at MGM Medical College and Hospital, Navi Mumbai, Maharashtra, India.
Materials and Methods: This retrospective study was done in the Department of Immunohematology and Blood Transfusion (IHBT) at MGM Medical College and Hospital, Navi Mumbai, Maharashtra, India for period of four years from January 2017 to December 2020 (48 months). Screening for anti-Human Immunodeficiency Virus (HIV)-1/2, anti-Hepatitis C Virus (HCV), and Hepatitis B surface Antigen (HBsAg), Venereal Disease Research Laboratory (VDRL) for syphilis, and slide test for malaria were done. Data was collected from various registers within the blood centre. It was entered in MS Excel spreadsheets and calculation was done for calculating the prevalence. R-square value was used to determine the trend of TTIs.
Results: A total of 19,864 donors were analysed for prevalence of TTIs from 2017 to 2020. Of these 99.16% were voluntary donors and 0.84% were replacement donors. Prevalence of TTI in total donors was 1.11%. Prevalence of hepatitis B was highest (0.84%) followed by syphilis (0.11%), HIV (0.07) and HCV (0.09) and malaria (0%). Prevalence was more in male replacement donors.
Conclusion: The prevalence of TTI in total donors was 1.11%. The number of total blood donations has been on the rise. Cases of HCV were steadily declining, but HIV, HBsAg, and syphilis showed a non linear trend. Strict adherence to the donor selection rules is needed to supply quality and safe blood to the patient.
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