Original article / research
Year : 2013 Month : July-September Volume : 2 Issue : 3 Page : 16 - 19

Asymptomatic bacteriuria among patients with Diabetes mellitus at a tertiary care center
 
Correspondence Address :
Dr. Shashidhar Vishwanath,
Associate Professor, Department of Microbiology,
Kasturba Medical College, Manipal University,
Manipal-576104, Karnataka, India.
Email: drshashidharv@gmail.com
Ph: + 91 9886075904, Fax: + 91 820 2571927
Objective:Patients with diabetes mellitus have a higher prevalence of asymptomatic bacteriuria and incidence of urinary tract infections compared to patients without diabetes mellitus. A prospective pilot study was conducted to determine the frequency of association of asymptomatic bacteriuria among patients with diabetes mellitus in comparison to control group without diabetes mellitus.

Methods:Urine specimens were processed by microscopy and culture following standard guidelines. The spectrum of uro-pathogens causing asymptomatic bacteriuria and their antibiotic susceptibility profile were noted.

Results:Asymptomatic bacteriuria was seen more commonly in patients with diabetes mellitus (4%) than in healthy control subjects. Asymptomatic bacteriuria was not seen in the non - diabetic individuals under control grou p . Three out of the four patients with asymptomatic bacteriuria had associated complications of diabetes mellitus. Enterococcusfaecalis( 2,50%),Staphylococcus saprophyticus (1, 25%) and Escherichia coli (1, 25%) were the organisms isolated from patients with asymptomatic bacteriuria. Staphylococcus saprophyticus isolate was mostly sensitive to antimicrobials tested. Enterococcus faecalis was sensitive to ampicillin. Escherichia coli isolate was multi-drug resistant.

Conclusion: Asymptomatic bacteriuria was more common among patients with diabetes mellitus than in healthy control subjects. Further, long term studies investigating the occurrence of complications secondary to asymptomatic bac te r iur ia in patie nts with diab ete s me llitu s a nd r a ndomize d control studies for studying the efficacy of antimicrobial therapy in preventing further complications in diabetes mellitus patients in Indian setups are needed.
 
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